NARROW-BAND IMAGING (NBI) FOR IMPROVING THE ASSESSMENT OF VOCAL FOLD LEUKOPLAKIA AND OVERCOMING THE UMBRELLA EFFECT.

It is crucial to find a balance between functional and oncological outcome when choosing an adequate method for the management of vocal fold leukoplakia.Therefore, a detailed examination is a milestone in the decision-making process.To examine whether narrow-band imaging (NBI) can be helpful in vocal fold assessment in the case of leukoplakia and h

Lysine63-linked ubiquitin (K63-Ub) chains represent a particular ubiquitin topology that mediates proteasome-independent signaling events.The deubiquitinating enzyme (DUB) BRCC36 segregates into distinct nuclear and cytoplasmic complexes that are specific for K63-Ub hydrolysis.RAP80 targets the five-member nuclear BRCC36 complex to K63-Ub chains at